Pioneering Non-Invasive Brain-Computer Interfaces to Revolutionize Mobility for Neuromuscular Injuries & Disorders
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Empowering lives through Nano-Biotechnology, without permanent invasive brain surgery
Galiana Technology Inc. is dedicated to transforming the lives of individuals with neuromuscular injuries and disorders due to spinal cord injuries, ALS, limb loss, diabetes, and more. We envision a future where groundbreaking neurological solutions are accessible, safe, and profoundly life-changing.
Millions face these debilitating challenges, with current brain-computer interface (BCI) solutions often requiring invasive brain surgery to implant electrodes that reliably record only a few dozen neurons, and then gradually lose function when the brain recognizes it as a foreign object. Galiana is poised to change this paradigm.
The human brain encodes specific movements through activating intricate fleeting "patterns" of sparsely distributed neurons, or ensembles, similar to how information is stored in pixel arrangements of QR codes. Recording millions of neurons in these ensembles would allow disabled individuals to control limbs or prosthetics with near-normal precision. To achieve this, we are developing nanofids—micron-sized intracellular electronic calcium sensors capable of single-neuron resolution recordings of all neurons across the cortex. When neurons are activated, nanofids emit unique near-infrared codes that are captured by a non-invasive optical fiber array and decoded via solid-state systems, converting neural activity into high-speed digital signals for real-time AI-driven analysis and motor control.
Unlike conventional approaches, our innovative solution achieves direct intra-neuronal communication without the need for chronic, permanently implanted probes.
Our patented Intracellular Monitoring Devices (IMDs) (U.S. Patent #12268512-B2) called nanofids are introduced using temporary micro-needling technology. Once inserted, nanofids are absorbed inside neurons and the system becomes a silent observer—ultralight, motion-tolerant, requiring no genetic manipulation and minimal signal processing. And unlike the probes of today that struggle to interface with the living brain, intracellular nanofids whisper their messages without continuing tissue damage or being rejected , meaning:
Our foundational technology is rigorously validated through:
Galiana Technology Inc. is driven by a powerful synergy of seasoned leadership and cutting-edge engineering expertise:
The global market for neuromuscular solutions and assistive technologies represents a significant and growing opportunity. By offering a dramatically less invasive and highly precise BCI, Galiana aims to unlock new possibilities for patient populations previously unreachable or hesitant due to long-term surgical implants.
Our technology's versatility, supported by collaborations like NIH-NIDA, also positions Galiana to address a wider spectrum of neurological challenges, from motor control to potential interventions for complex neural disorders. We are not just building a product; we are laying the foundation for a future where advanced brain interfaces empower greater independence and enhance human well-being on an unprecedented scale.
What if we could read the full language of thought—not just fragments, but the complex symphony of abstract ideas, memories, emotions, and intentions that define what it means to be human?
To achieve this, we must move beyond today’s limits and imagine a system capable of recording binarized neural activity from all 30 billion neurons in the human cortex. The human brain encodes meaning not through bulk activity, but via intricate, fleeting “patterns” of sparsely distributed neurons—neuronal ensembles—analogous to the pixel arrangements that encode information in a QR code. Each ensemble is a unit of thought, and with enough of them, AI can begin to map the living architecture of cognition. But there’s a problem. Today’s technologies—electrode arrays and calcium imaging—capture mere thousands of neurons at best in freely moving animals, and even fewer in humans. Biological and physical constraints make it virtually impossible for them to ever reach beyond 0.01% to 0.1% of neurons in the cortex. The resolution we need to decode full cognition has been out of reach... Until now.
We are pioneering a breakthrough system based on intracellular, one-micron-sized sensors called nanofids—a radically new interface technology that aims to reach every neuron in the human cortex with single-neuron resolution. Each nanofid responds to neural activity by emitting a unique near-infrared (NIR) optical code, serving as a digital beacon of that neuron’s activation. This NIR signal is then captured by a non-invasive optical fiber array and rapidly decoded using a solid-state optical sorting system, converting biological activity into high-speed digital signals ready for real-time AI analysis.
Once inserted, the system becomes a silent observer—ultralight, motion-tolerant, requiring no genetic manipulation and minimal signal processing. And unlike the probes of today that struggle to interface with the living brain, nanofids whisper their messages without damaging tissue or being rejected.
This is not just a brain-computer interface. It is a neural mirror—one that reflects the true complexity and resolution of the human mind in real time and unlocks a new era of cognitive symbiosis between humans and AI.
We’re not just reading signals. We’re decoding consciousness.
Galiana Technology Inc. is actively seeking strategic investment to accelerate our pre-clinical development, expand our research capabilities, and advance towards human clinical trials.
Join us in shaping the future of neuro-rehabilitation and beyond.
US Patent 11,627,907: Method and System for the Capture of Intra-Cellular Activity
US Patent 12,268,512: Method and System for the Capture of Intra-Cellular Activity
US Patent Application 9/799,904: Method and System for the Capture of Intra-Cellular Activity with Nanofids
DARPA DSO Grant # D18AP0062
Galiana Technologies and UCSD collaborator (Dr. Oscar Vazquez Mena) obtained funding from July 2021 – June 2023 for nanofid development including: reduction of all component sizes to 10-100 microns; manufacture and testing of calcium sensor; end-to-end simulations demonstrating feasibility of design, power, and signal processing.
See UCSD News Release for more info- https://jacobsschool.ucsd.edu/news/release/3258?id=3258#https://jacobsschool.ucsd.edu/news/release/3258%20
Friday, April 10th, 2015
San Diego, CA – Galiana Technology, an emerging growth company in the field of electronic R&D for neuroscience applications, received a grant on September 10, 2014. The grant was endowed by National Institutes of Health (NIH) for the purpose of developing an electrical circuit prototype for nanoscale intracellular neural recording.
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